Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis is a scholarly work by Antoine M van Oijen, Samir M. Hamdan, and Charles C. Richardson, published in 2008 in ''Nature''. The main subjects of the publication include DNA primase, biology, DNA polymerase processivity factor complex, DNA polymerase, primer, deoxyribonucleic acid, DnaG, Okazaki fragments, genetics, DnaA, DNA replication, replisome, cell biology, G-quadruplex, DNA repair, biophysics, and Prokaryotic DNA replication. In all organisms, the protein machinery responsible for the replication of DNA, the replisome, is faced with a directionality problem.