Does Hyperconcentration Result in Platelet Activation?
Does Hyperconcentration Result in Platelet Activation? is a scholarly work, published in 1998 in ''Vox Sanguinis''. The main subjects of the publication include immunology, internal medicine, platelet, fluid replacement, flow cytometry, medicine, blood transfusion, selectin P, chemistry, and blood coagulation. Abstract Background and Objectives: Hyperconcentration of platelets may lead to platelet activation and loss of platelet function. Materials and Methods: Platelet activation following hyperconcentration was assessed using flow‐cytometric detection of platelet P‐selectin expression and platelet swirling. Results: Platelet hyperconcentration led to a minimal increase in P‐selectin expression and no differnce in platelet swirling. Conclusion: Hyperconcentration was not associated with a clinically significant change in platelet activation and had no significant effect on platelet quality as detected by pH and platelet yield..