Dimethylmalate dehydrogenase
In enzymology, dimethylmalate dehydrogenase is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are -3,3-dimethylmalic acid and oxidised nicotinamide adenine dinucleotide. Its products are α-ketoisovaleric acid, carbon dioxide, reduced NADH, and a proton.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is -3,3-dimethylmalate:NAD+ oxidoreductase . This enzyme is also called beta,beta-dimethylmalate dehydrogenase. This enzyme participates in pantothenate and coa biosynthesis. It has 5 cofactors: ammonia, manganese, cobalt, potassium, and NH4+.