Cucurbitacin Delta23-reductase

In enzymology, cucurbitacin Delta23-reductase is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are the plant steroid curbitacin b, reduced nicotinamide adenine dinucleotide, and a proton. Its products are dihydrocucurbitacin b, and oxidised NAD⁺. The enzyme can use nicotinamide adenine dinucleotide phosphate as an alternative cofactor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 23,24-dihydrocucurbitacin:NAD+ Delta23-oxidoreductase. This enzyme is also called NADH: cucurbitacin B Delta23-oxidoreductase. It contains manganese.