Very-long-chain 3-oxoacyl-CoA synthase


Very-long-chain 3-oxoacyl-CoA synthase is an enzyme with systematic name malonyl-CoA:very-long-chain acyl-CoA malonyltransferase . This enzyme catalyses the following chemical reaction
This is the first component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA to very-long-chain acyl CoAs. (Very-long-chain in this context refers, for example, to the C26 fatty acids involved in the synthesis of phospholipids and ceramides.