Chromosome 16
Chromosome 16 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 16 spans about 90 million base pairs and represents just under 3% of the total DNA in cells.
Genes
Number of genes
The following are some of the gene count estimates of human chromosome 16. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies. Among various projects, the collaborative consensus coding sequence project takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.| Estimated by | Protein-coding genes | Non-coding RNA genes | Pseudogenes | Source | Release date |
| CCDS | 795 | — | — | 2016-09-08 | |
| HUGO [Gene Nomenclature Committee|HGNC] | 802 | 251 | 365 | 2017-05-12 | |
| Ensembl genome [database project|Ensembl] | 865 | 1,046 | 462 | 2017-03-29 | |
| UniProt | 838 | — | — | 2018-02-28 | |
| NCBI | 912 | 652 | 502 | 2017-05-19 |
Gene list
The following is a partial list of genes on human chromosome 16. For complete list, see the link in the infobox on the right.Diseases and disorders
- Attention deficit hyperactivity disorder
- Asperger syndrome
- Autism spectrum disorder
- Autosomal dominant polycystic kidney disease
- Batten disease
- Combined malonic and methylmalonic aciduria
- Familial Mediterranean fever
- Synesthesia
- Thalassemia
- Trisomy 16
- Morquio syndrome
- Hao-Fountain Syndrome
Associated traits
Cytogenetic band
| Chr. | Arm | Band | ISCN start | ISCN stop | Basepair start | Basepair stop | Stain | Density |
| 16 | p | 13.3 | 0 | 352 | gneg | |||
| 16 | p | 13.2 | 352 | 596 | gpos | 50 | ||
| 16 | p | 13.13 | 596 | 813 | gneg | |||
| 16 | p | 13.12 | 813 | 948 | gpos | 50 | ||
| 16 | p | 13.11 | 948 | 1070 | gneg | |||
| 16 | p | 12.3 | 1070 | 1246 | gpos | 50 | ||
| 16 | p | 12.2 | 1246 | 1409 | gneg | |||
| 16 | p | 12.1 | 1409 | 1558 | gpos | 50 | ||
| 16 | p | 11.2 | 1558 | 1856 | gneg | |||
| 16 | p | 11.1 | 1856 | 2045 | acen | |||
| 16 | q | 11.1 | 2045 | 2194 | acen | |||
| 16 | q | 11.2 | 2194 | 2709 | gvar | |||
| 16 | q | 12.1 | 2709 | 2953 | gneg | |||
| 16 | q | 12.2 | 2953 | 3142 | gpos | 50 | ||
| 16 | q | 13 | 3142 | 3346 | gneg | |||
| 16 | q | 21 | 3346 | 3657 | gpos | 100 | ||
| 16 | q | 22.1 | 3657 | 4023 | gneg | |||
| 16 | q | 22.2 | 4023 | 4118 | gpos | 50 | ||
| 16 | q | 22.3 | 4118 | 4294 | gneg | |||
| 16 | q | 23.1 | 4294 | 4551 | gpos | 75 | ||
| 16 | q | 23.2 | 4551 | 4659 | gneg | |||
| 16 | q | 23.3 | 4659 | 4768 | gpos | 50 | ||
| 16 | q | 24.1 | 4768 | 4930 | gneg | |||
| 16 | q | 24.2 | 4930 | 5025 | gpos | 25 | ||
| 16 | q | 24.3 | 5025 | 5120 | gneg |