Chromosome 14

Chromosome 14 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 14 spans about 107 million base pairs and represents between 3 and 3.5% of the total DNA in cells.
The centromere of chromosome 14 is positioned approximately at position 17.2 Mbp.

Genes

Number of genes

The following are some of the gene count estimates of human chromosome 14. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies. Among various projects, the collaborative consensus coding sequence project takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.

Estimated by	Protein-coding genes	Non-coding RNA genes	Pseudogenes	Source	Release date
CCDS	583	—	—		2016-09-08
HUGO [Gene Nomenclature Committee\|HGNC]	593	324	513		2017-05-12
Ensembl genome [database project\|Ensembl]	820	856	518		2017-03-29
UniProt	720	—	—		2018-02-28
NCBI	621	690	598		2017-05-19

Gene list

The following is a partial list of genes on human chromosome 14. For complete list, see the link in the infobox on the right.

Diseases and disorders

The following diseases are some of those related to genes on chromosome 14:

Cytogenetic band

Chr.	Arm	Band	ISCN start	ISCN stop	Basepair start	Basepair stop	Stain	Density
14	p	13	0	284			gvar
14	p	12	284	624			stalk
14	p	11.2	624	1249			gvar
14	p	11.1	1249	1433			acen
14	q	11.1	1433	1660			acen
14	q	11.2	1660	2043			gneg
14	q	12	2043	2313			gpos	100
14	q	13.1	2313	2469			gneg
14	q	13.2	2469	2582			gpos	50
14	q	13.3	2582	2724			gneg
14	q	21.1	2724	2923			gpos	100
14	q	21.2	2923	3008			gneg
14	q	21.3	3008	3264			gpos	100
14	q	22.1	3264	3491			gneg
14	q	22.2	3491	3604			gpos	25
14	q	22.3	3604	3718			gneg
14	q	23.1	3718	3916			gpos	75
14	q	23.2	3916	4044			gneg
14	q	23.3	4044	4186			gpos	50
14	q	24.1	4186	4484			gneg
14	q	24.2	4484	4626			gpos	50
14	q	24.3	4626	4839			gneg
14	q	31.1	4839	5051			gpos	100
14	q	31.2	5051	5094			gneg
14	q	31.3	5094	5349			gpos	100
14	q	32.11	5349	5406			gneg
14	q	32.12	5406	5505			gpos	25
14	q	32.13	5505	5619			gneg
14	q	32.2	5619	5732			gpos	50
14	q	32.31	5732	5903			gneg
14	q	32.32	5903	6016			gpos	50
14	q	32.33	6016	6300			gneg