Chromosome 10
Chromosome 10 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 10 spans about 134 million base pairs and represents between 4 and 4.5 percent of the total DNA in cells.
Genes
Number of genes
The following are some of the gene count estimates of human chromosome 10. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies. Among various projects, the collaborative consensus coding sequence project takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.| Estimated by | Protein-coding genes | Non-coding RNA genes | Pseudogenes | Source | Release date |
| CCDS | 706 | — | — | 2016-09-08 | |
| HUGO [Gene Nomenclature Committee|HGNC] | 708 | 244 | 614 | 2017-05-12 | |
| Ensembl | 728 | 881 | 568 | 2017-03-29 | |
| UniProt | 750 | — | — | 2018-02-28 | |
| NCBI | 754 | 842 | 654 | 2017-05-19 |
Gene list
The following is a partial list of genes on human chromosome 10. For complete list, see the link in the infobox on the right.Diseases and disorders
The following diseases are related to genes on chromosome 10:- Apert syndrome
- Barakat syndrome
- Beare–Stevenson cutis gyrata syndrome
- Charcot–Marie–Tooth disease
- Cockayne syndrome
- Congenital erythropoietic porphyria
- Cowden syndrome
- Crouzon syndrome
- Genitopatellar syndrome
- Glioblastoma multiforme
- Gorlin syndrome
- HADDS syndrome
- Hermansky–Pudlak syndrome
- Hirschprung disease
- Jackson–Weiss syndrome
- Multiple endocrine neoplasia type 2
- Nonsyndromic deafness
- Pfeiffer syndrome
- Porphyria
- Spondyloepimetaphyseal dysplasia, Pakistani type
- Tetrahydrobiopterin deficiency
- Thiel–Behnke corneal dystrophy
- Usher syndrome
- Wolman syndrome
- Young-Simpson syndrome
- Combined Saposin Deficiency
Cytogenetic band
| Chr. | Arm | Band | ISCN start | ISCN stop | Basepair start | Basepair stop | Stain | Density |
| 10 | p | 15.3 | 0 | 229 | gneg | |||
| 10 | p | 15.2 | 229 | 329 | gpos | 25 | ||
| 10 | p | 15.1 | 329 | 630 | gneg | |||
| 10 | p | 14 | 630 | 917 | gpos | 75 | ||
| 10 | p | 13 | 917 | 1175 | gneg | |||
| 10 | p | 12.33 | 1175 | 1361 | gpos | 75 | ||
| 10 | p | 12.32 | 1361 | 1432 | gneg | |||
| 10 | p | 12.31 | 1432 | 1604 | gpos | 75 | ||
| 10 | p | 12.2 | 1604 | 1662 | gneg | |||
| 10 | p | 12.1 | 1662 | 1891 | gpos | 50 | ||
| 10 | p | 11.23 | 1891 | 2063 | gneg | |||
| 10 | p | 11.22 | 2063 | 2235 | gpos | 25 | ||
| 10 | p | 11.21 | 2235 | 2406 | gneg | |||
| 10 | p | 11.1 | 2406 | 2621 | acen | |||
| 10 | q | 11.1 | 2621 | 2850 | acen | |||
| 10 | q | 11.21 | 2850 | 3051 | gneg | |||
| 10 | q | 11.22 | 3051 | 3252 | gpos | 25 | ||
| 10 | q | 11.23 | 3252 | 3409 | gneg | |||
| 10 | q | 21.1 | 3409 | 3753 | gpos | 100 | ||
| 10 | q | 21.2 | 3753 | 3839 | gneg | |||
| 10 | q | 21.3 | 3839 | 4097 | gpos | 100 | ||
| 10 | q | 22.1 | 4097 | 4469 | gneg | |||
| 10 | q | 22.2 | 4469 | 4655 | gpos | 50 | ||
| 10 | q | 22.3 | 4655 | 4970 | gneg | |||
| 10 | q | 23.1 | 4970 | 5200 | gpos | 100 | ||
| 10 | q | 23.2 | 5200 | 5331 | gneg | |||
| 10 | q | 23.31 | 5331 | 5558 | gpos | 75 | ||
| 10 | q | 23.32 | 5558 | 5672 | gneg | |||
| 10 | q | 23.33 | 5672 | 5887 | gpos | 50 | ||
| 10 | q | 24.1 | 5887 | 5973 | gneg | |||
| 10 | q | 24.2 | 5973 | 6131 | gpos | 50 | ||
| 10 | q | 24.31 | 6131 | 6202 | gneg | |||
| 10 | q | 24.32 | 6202 | 6317 | gpos | 25 | ||
| 10 | q | 24.33 | 6317 | 6374 | gneg | |||
| 10 | q | 25.1 | 6374 | 6646 | gpos | 100 | ||
| 10 | q | 25.2 | 6646 | 6761 | gneg | |||
| 10 | q | 25.3 | 6761 | 6890 | gpos | 75 | ||
| 10 | q | 26.11 | 6890 | 7090 | gneg | |||
| 10 | q | 26.12 | 7090 | 7219 | gpos | 50 | ||
| 10 | q | 26.13 | 7219 | 7506 | gneg | |||
| 10 | q | 26.2 | 7506 | 7721 | gpos | 50 | ||
| 10 | q | 26.3 | 7721 | 8050 | gneg |