Caldalkalibacillus
Caldalkalibacillus is an aerobic and spore-forming genus of bacteria from the family Bacillaceae the stains either Gram-positive or Gram-variable. The type species of this genus is Caldalkalibacillus thermarum.
Caldalkalibacillus ''mannanilyticus was previously a species belonging to Bacillus, a genus that has been recognized as displaying extensive polyphyly and has been restricted by recent phylogenetic studies to only include species closely related to Bacillus subtilis and Bacillus cereus.
The name Caldalkalibacillus is derived from the prefix "-caldalkali", and the suffix "-bacillus".
Biochemical characteristics and molecular signatures
Members of this genus are aerobic and some are motile and endospore-forming. Colonies formed are either yellow or yellowish-white in colour. Temperature range for growth is 20–65°C, with optimum growth temperature for C. mannanilyticus around 37°C, whereas C. thermarum grows optimally at 60°C. The pH range for growth is 7.5–10, with optimal growth occurring around pH 8.5–9.0.Four conserved signature indels were identified through genomic analyses for this genus in the following proteins: prephenate dehydrogenase, isoprenyl transferase, DUF1027 domain-containing protein and adenine deaminase, which in most cases are exclusively shared by either all or most members of this genus. These CSIs provide a reliable molecular means of distinguishing Caldalkalibacillus species from other Bacillaceae genera and bacteria.