C8 complex


Complement component 8 is a protein involved in the complement system. It is part of the membrane attack complex.
A hereditary deficiency of C8 can result in increased susceptibility to Neisseria infections, such as meningitis and gonorrhea.
Image:Formowanie MAC.svg|thumb|400px|top|Membrane attack complex. Some labels are in Polish.

Structure

C8 is a heterotrimer; it consists of three different subunits. These are called C8 alpha, beta and gamma chains, encoded by the genes C8A, C8B and C8G respectively.