Writing in the Daily Express, Michelle Davies rated the book 4/5 and said Bones are Forever would make readers "want to keep turning the pages long after lights out to find out what happens next." but that the forensic details provide by Reiches meant some scenes "drag like a science textbook". Entertainment Weekly gave the novel a B−, saying that "If you can get past the lab jargon" the novel was a "decent detective yarn". The Irish Independent called it a "genuinely gripping tale" that is "peppered with authentic forensic science and peopled with well drawn, rounded characters." Publishers Weekly said that Reichs had delivered a "pulse-pounding story".