BitterDB
The BitterDB is a database of compounds that were reported to taste bitter to humans. The aim of the BitterDB database is to gather information about bitter-tasting natural and synthetic compounds, and their cognate bitter taste receptors.
Summary
The BitterDB includes over 670 compounds that were reported to taste bitter to humans. The compounds can be searched by name, chemical structure, similarity to other bitter compounds, association with a particular human bitter taste receptor, and by other properties as well. The database also contains information on mutations in bitter taste receptors that were shown to influence receptor activation by bitter compounds.Database overview
Bitter compounds
BitterDB currently contains more than 670 compounds that were cited in the literature as bitter. For each compound, the database offers information regarding its molecular properties, references for the compound’s bitterness, including additional information about the bitterness category of the compound, different compound identifiers, an indication whether the compound is derived from a natural source or is synthetic, a link to the compound’s PubChem entry and different file formats for downloading.Over 200 bitter compounds have been experimentally linked to their corresponding human bitter taste receptors. For those compounds, BitterDB provides additional information, including links to the publications indicating these ligand–receptor interactions, the effective concentration for receptor activation and/or the EC50 value and links to the associated bitter taste receptors entries in the BitterDB.