BCL7A

B-cell CLL/lymphoma 7 protein family member A is a protein that in humans is encoded by the BCL7A gene located in the chromosome 12.

Function

This gene codifies for a protein that belongs to the SWI/SNF chromatin remodelling complex, a complex that is able to modify the interactions between DNA and histones using the energy of the ATP hydrolysis. It has found recurrently mutated in lymphomas and silenced by promoter hypermetylation in haematological malignancies.