BCL7A

B-cell CLL/lymphoma 7 protein family member A is a protein that in humans is encoded by the BCL7A gene located in the chromosome 12.

Function

This gene codifies for a protein that belongs to the SWI/SNF chromatin remodelling complex, a complex that is able to modify the interactions between DNA and histones using the energy of the ATP hydrolysis. It has found recurrently mutated in Diffuse large [B-cell lymphoma|lymphomas] and silenced by promoter hypermetylation in haematological malignancies.