Automated Analysis of Single-Molecule Photobleaching Data by Statistical Modeling of Spot Populations
Automated Analysis of Single-Molecule Photobleaching Data by Statistical Modeling of Spot Populations is a scholarly work by Dirk-Peter Herten, Kristin S Grussmayer, and Roland Eils, published in 2015 in ''Biophysical Journal''. The main subjects of the publication include photobleaching, fluorescence, fluorescence microscope, protein microarray, molecule, fluorophore, noise, Analytical Chemistry, Bioimage informatics, biological system, statistics, chemistry, population, and fluorescence recovery after photobleaching. The authors propose a new approach, to the authors' knowledge, to determine the fluorophore number that correlates the intensity decay of a population of molecule complexes with the decay of the number of visible complexes.