Andy Isabella


Andy Isabella is an American professional football wide receiver. He played college football for the UMass Minutemen, and was selected by the Arizona Cardinals in the second round of the 2019 NFL draft.

Early life

Isabella attended Mayfield High School in Mayfield, Ohio. Isabella ran track in high school. In his senior year of high school, Isabella won the state title in the 100-meter dash, beating fellow sprinter and future Cleveland Browns cornerback Denzel Ward in a close race. He committed to the University of Massachusetts to play college football. Isabella is of Italian heritage.

College career

Isabella played at UMass from 2015 to 2018. Initially recruited as a running back, he converted to wide receiver his sophomore year. During his career he had 231 receptions for 3,526 yards and 30 touchdowns. As a senior, he was an All-American and was a finalist for the Fred Biletnikoff Award.
In 2018, he led the country in receiving yards per game and was named to the 2018 College Football All-America Team. Isabella was Pro Football Focus's highest rated wide receiver in college football, posting a season grade of 93.2.

College statistics

Statistics

Professional career

Pre-draft

Isabella declared for the 2019 NFL draft after his senior season. At the combine, Isabella ran a 4.31 second 40 yard dash, which was the third fastest time at that year's combine, tied with Ohio State wide receiver Parris Campbell.

Arizona Cardinals

Isabella was drafted by the Arizona Cardinals with the 62nd overall pick in the second round of the draft. The Cardinals acquired this selection in a trade that sent Josh Rosen to the Miami Dolphins. In Week 9 against the San Francisco 49ers, Isabella caught one pass for an 88-yard touchdown in the 28-25 loss. This was Isabella's first career receiving touchdown in the NFL. He finished his rookie season with nine receptions for 189 receiving yards and one receiving touchdown.
In Week 3 of the 2020 season, Isabella recorded four receptions for 47 receiving yards and two touchdowns in the 26–23 loss to the Detroit Lions.
Isabella entered the 2021 season sixth on the Cardinals wide receiver depth chart, and only had one catch the entire season and was inactive for half the season.
On October 4, 2022, the Cardinals waived Isabella.

Baltimore Ravens

On October 10, 2022, Isabella signed with the practice squad of the Baltimore Ravens. On December 31, 2022, Isabella was elevated to Baltimore's active roster for Week 17 versus the Pittsburgh Steelers. On January 2, 2023, Isabella was put back on Baltimore's practice squad after a thigh injury versus Pittsburgh. On January 14, 2023, Isabella was elevated to Baltimore's active roster again for their playoff game versus the Cincinnati Bengals. He signed a reserve/future contract on January 19, 2023. He was released on July 25, 2023.

Buffalo Bills

On July 28, 2023, Isabella signed with the Buffalo Bills. He was waived on August 29, 2023, and re-signed to the practice squad. During the season, Isabella played in only two regular season games, and two playoff games. He signed a reserve/future contract on January 22, 2024. He was released on August 27, 2024.

St. Louis Battlehawks (first stint)

On October 2, 2024, Isabella signed with the St. Louis Battlehawks of the United Football League.

Pittsburgh Steelers

On October 25, 2024, Isabella signed with the Pittsburgh Steelers practice squad. He was released on November 5.

St. Louis Battlehawks (second stint)

Isabella was re-signed by the Battlehawks on December 20, 2024. He was released on March 20, 2025.

San Francisco 49ers

On July 31, 2025, Isabella signed with the San Francisco 49ers. He was released on August 5.

NFL career statistics

Regular season

Coaching career

Isabella signed with Athletes Untapped as a private football coach on Sep 8, 2025.