Anadarko, TexasAnadarko is an unincorporated community in Rusk County, Texas, United States. According to the Handbook of Texas, the community had a population of 30 in 2000.GeographyAnadarko is located on Farm to Market Road 1662, southwest of Henderson in southwestern Rusk County. U.S. Route 84 exits into Anadarko on Farm to Market Road 2753.