Amino acid score


Amino acid score is used to determine if a protein is complete. It is used along with the measure of protein digestibility that refers to how well a given protein is digested, to compare the proportion of essential amino acids found in one protein to the proportion in a "reference protein" considered to be complete.

Methods of amino acid score calculation

PDCAAS and DIAAS are the two major protein standards which determine the completeness of proteins by their unique composition of essential amino acids.

Simple AAS, PDCAAS

PDCAAS considers digestibility and AAS separately. It has a single "reference protein" profile, in which the amounts in milligrams of each essential amino acid in each gram of the reference protein is listed. To find the AAS given the amino acid profile of the test protein and the amino acid profile of the reference protein :
PDCAAS estimates digestibility in a separate procedure. The estimated PD is multiplied with AAS to get PDCAAS.

Digestibility-corrected AAS, DIAAS

DIAAS considers the profile of the essential amino acids that are actually absorbed. This value is calculated by estimating the amount of each EAA absorbed in the "test protein" by comparing how much of each EAA went into the mouth and how much was pumped out of the end of the small intestines. This was then turned into a profile by dividing the amounts in milligrams of each EAA with the grams of the test protein eaten. From then on, the calculation is similar:
  • For each essential amino acid, calculate.
  • Take the amino acid with the smallest value of. Call it. This is the limiting amino acid taking actual absorption into account.
  • The DIAAS is.
DIAAS provides three separate reference profiles for different human age groups.