Amdoparvovirus


Amdoparvovirus is a genus of viruses in the family Parvoviridae in the subfamily Parvovirinae. Mustelids, skunk, and raccoons serve as natural hosts. There are 11 species in this genus. Diseases associated with this genus include progressive disorder of immune system.

Taxonomy

The genus contains the following species, listed by scientific name and followed by the exemplar virus of the species:Amdoparvovirus carnivoran1, Aleutian mink disease parvovirusAmdoparvovirus carnivoran2, Gray [fox amdovirus]Amdoparvovirus carnivoran3, Racoon dog and fox amdoparvovirusAmdoparvovirus carnivoran4, Skunk amdoparvovirusAmdoparvovirus carnivoran5, Red panda amdoparvovirusAmdoparvovirus carnivoran6, Labrador amdoparvovirus 1Amdoparvovirus carnivoran7, Red panda amdoparvovirus 2Amdoparvovirus carnivoran8, British Columbia amdoparvovirusAmdoparvovirus carnivoran9, Aleutian mink disease virus 2Amdoparvovirus carnivoran10, Aleutian mink disease virus 3Amdoparvovirus chiropteran1, Sabeidhel virus 1

Structure

Viruses in the genus Amdoparvovirus have non-enveloped protein particles with T=1 icosahedral symmetry. They are around 18 to 26 nm in diameter and contain a single linear single-stranded DNA genome around 4.8 kb in length.
GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
AmdoparvovirusIcosahedralT=1Non-envelopedLinear-

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, which mediate clathrin-mediated endocytosis. Replication follows the rolling-hairpin model. DNA templated transcription, with some alternative splicing mechanism is the method of transcription. The virus may exit the host cell by vesicular trafficking following nuclear pore export or be released following cell lysis.
Mustelids, skunk, and raccoons serve as the natural host. Transmission routes are oral and respiratory.
GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
AmdoparvovirusMammals: minks, ferrets, foxes-Clathrin-mediated endocytosisVesicular export or cell lysisNucleusNucleusUnknown