Alanine dehydrogenase
Alanine dehydrogenase is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are alanine, water, and oxidised nicotinamide adenine dinucleotide. Its products are pyruvic acid, reduced NADH, ammonia, and a proton.
This enzyme participates in taurine and hypotaurine metabolism and reductive carboxylate cycle.
Nomenclature
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-alanine:NAD+ oxidoreductase. Other names in common use include AlaDH, L-alanine dehydrogenase, NAD+-linked alanine dehydrogenase, alpha-alanine dehydrogenase, NAD+-dependent alanine dehydrogenase, alanine oxidoreductase, and NADH-dependent alanine dehydrogenase. T
Structure
Alanine dehydrogenase contains both a N-terminus and C-terminus domains.