Acylglycerone-phosphate reductase

In enzymology, acylglycerone-phosphate reductase is an enzyme that catalyzes the chemical reaction
The substrate of this enzyme is an ester of the long-chain fatty acid,, which reacts with oxidised nicotinamide adenine dinucleotide phosphate. This converts the hydroxy group of the glycerol fragment to the corresponding ketone. The cofactor is converted to NADPH, and a proton is released.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 1-palmitoylglycerol-3-phosphate:NADP⁺ oxidoreductase. Other names in common use include palmitoyldihydroxyacetone-phosphate reductase, palmitoyl dihydroxyacetone phosphate reductase, palmitoyl-dihydroxyacetone-phosphate reductase, acyldihydroxyacetone phosphate reductase, and palmitoyl dihydroxyacetone phosphate reductase. This enzyme participates in glycerophospholipid and ether lipid metabolism.