A Network Model of the Molecular Organization of Chromatin in Drosophila
A Network Model of the Molecular Organization of Chromatin in Drosophila is a scholarly work by Bas van Steensel, Fred van Leeuwen, and Guillaume J Filion, published in 2013 in ''Molecular Cell''. The main subjects of the publication include ChIP-sequencing, gene regulatory network, histone-modifying enzymes, genetics, chromatin, Drosophila, epigenetics, scaffold/matrix attachment region, gene, ChIA-PET, computational biology, proteome, cell biology, chromatin remodeling, Bivalent chromatin, ChIP on chip, and biology. The authors demonstrate functional compartmentalization of this network, and predict functions for most of the previously unknown chromatin proteins, including roles in DNA replication and repair, and gene activation and repression.