ADL-5747
ADL-5747 was a novel opioid analgesic drug, however its development was halted because it did not pass phase II trials.
Mechanism of action
ADL-5747 is an opioid analgesic, it works by activating opioid receptors. However, unlike "classical" opioids such as morphine, it is selective for the delta receptor.In tests done on mice, ADL-5747 was able to reduce pain in an efficient way. This compound does not seem to cause receptor internalization.