5-MeO-MPMI
5-MeO-MPMI, also known as 5-methoxy-N-methyl-tryptamine, is a psychedelic drug of the pyrrolidinylmethylindole and cyclized tryptamine families.
Pharmacology
Pharmacodynamics
5-MeO-MPMI produces psychedelic-appropriate responding in animal tests, with similar potency to DOI. It has two enantiomers, with only the -enantiomer being active.
Chemistry
Analogues
Analogues of 5-MeO-MPMI include MPMI, 4-HO-MPMI, 5-fluoro-MPMI, 5-MeO-pyr-T, CP-122288, CP-135807, and eletriptan, among others.
History
5-MeO-MPMI was first developed by the team led by J. E. Macor and colleagues in 1992. It was subsequently investigated by the team led by David E. Nichols from Purdue University in the late 1990s.
Canada
5-MeO-MPMI is not a controlled substance in Canada as of 2025.