3beta-hydroxy-5beta-steroid dehydrogenase
In enzymology, 3beta-hydroxy-5beta-steroid dehydrogenase is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are epipregnanolone and oxidised nicotinamide adenine dinucleotide phosphate. Its products are 5β-dihydroprogesterone, reduced NADPH, and a proton.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3beta-hydroxy-5beta-steroid:NADP+ 3-oxidoreductase. Other names in common use include 3beta-hydroxysteroid 5beta-oxidoreductase, and 3beta-hydroxysteroid 5beta-progesterone oxidoreductase.