3,4-Ethylenedioxymethcathinone

3,4-Ethylenedioxymethcathinone, also known as EDMC or 3,4-ethylenedioxy-N-methylcathinone, is a monoamine releasing agent of the phenethylamine, EDxx, and cathinone families related to methylone. It is the β-keto or cathinone analogue of 3,4-ethylenedioxymethamphetamine.
EDMC acts as a serotonin–norepinephrine–dopamine releasing agent. Its values for induction of monoamine release are 347nM for serotonin, 327nM for norepinephrine, and 496nM for dopamine in rat brain synaptosomes. These potencies were about 1.4-fold, 2.2-fold, and 3.7-fold lower than those of methylone, respectively.
The drug was first described in 2015, whereas EDMA has been described much earlier.