2C-B-OH

2C-B-OH, also known as 4-bromo-2,5-dimethoxy-N-hydroxyphenethylamine or as N-hydroxy-2C-B, is a chemical compound of the phenethylamine and 2C families related to the psychedelic drug 2C-B. It is the N-hydroxy derivative of 2C-B and is structurally related to the HOT-x psychedelics like HOT-2, HOT-7, and HOT-17. Unlike the HOT-x drugs however, 2C-B-OH was not included nor mentioned by Alexander Shulgin in his 1991 book PiHKAL. The HOT-x psychedelics, as well as the MDxx entactogens MDOH and FLEA, may act as prodrugs of their N-unsubstituted analogues, for instance HOT-2 into 2C-T-2. The chemical synthesis of 2C-B-OH has been described. The drug was first described in the scientific literature by Leth-Petersen and colleagues in 2016. It is a controlled substance in Canada under phenethylamine blanket-ban language.