25I-NBF


25I-NBF is a derivative of the phenethylamine hallucinogen 2C-I, which acts as a highly potent partial agonist for the human 5-HT2A receptor, with bias towards the β-arrestin 2 coupled signalling pathway. It has been studied in its 11C radiolabelled form as a potential ligand for mapping the distribution of 5-HT2A receptors in the brain, using positron [emission tomography].

Society and culture

Legal status

25I-NBF is illegal in Hungary, Japan, Latvia, and Vermont.

Sweden

added 25I-NBF to Narcotic Drugs Punishments Act under Swedish schedule I as of January 26, 2016, published by Medical Products [Agency (Sweden)|Medical Products Agency (MPA)] in regulation HSLF-FS 2015:35 listed as 25I-NBF, and 2--N-etanamin.

United Kingdom