22nd Independent Spirit Awards
The 22nd Independent Spirit Awards, honoring the best independent films of 2006, were presented on February 24, 2007. The nominations were announced on November 28, 2006. Sarah Silverman returned as host for the second consecutive year.
Winners and nominees
Films with multiple nominations and awards
| Nominations | Film |
| 6 | Half Nelson |
| 5 | Little Miss Sunshine |
| 3 | American Gun |
| 3 | The Dead Girl |
| 3 | A Guide to Recognizing Your Saints |
| 3 | Man Push Cart |
| 2 | Day Night Day Night |
| 2 | Four Eyed Monsters |
| 2 | Friends with Money |
| 2 | The Painted Veil |
| 2 | Pan's Labyrinth |
| 2 | Sorry, Haters |
| 2 | Sweet Land |
| 2 | Thank You for Smoking |
| 2 | Wristcutters: A Love Story |
| Awards | Film |
| 4 | Little Miss Sunshine |
| 2 | Half Nelson |
Special awards
[Independent Spirit [John Cassavetes Award|John Cassavetes Award]]
Quinceañera12 and HoldingChalkFour Eyed Monsters- ''Old Joy''
Truer Than Fiction Award
Adele Horne – The Tailenders- Eric Daniel Metzgar – The Chances of the World Changing
- A. J. Schnack – ''Kurt Cobain: About a Son''
Producers Award
Howard Gertler and Tim Perell - Pizza and Shortbus- Julie Lynn - 10 Items or Less and Nine Lives
- Alex Orlovsky and Jamie Patricof - Half Nelson and ''Point&Shoot''