2025 in Missouri

The following is a list of events of the year 2025 in Missouri.

Incumbents

January 5 – Missouri is affected by the January 5–6, 2025 United States blizzard.
April 8 – 2025 St. Louis mayoral election: Cara Spencer beats incumbent mayor Tishaura Jones in a rematch of the 2021 election.
April 18 – 2025 Southwest United States measles outbreak: The Missouri Health Department confirms the state's first case of measles in 2025.
May 16 – Seven people are killed by storms, including five in St. Louis County.
May 27 – The Missouri Supreme Court orders a new ruling in a lower court decision related to the state's abortion ban. The state Supreme Court's decision effectively bans abortions in Missouri.
June 14 – 2025 UFL championship game
December 4 – An appeals court rules Missouri must reword Amendment 3, a proposed 2026 ballot measure that would ban most abortions in the state. A judge says the current wording falsely implies the measure would create new guarantees of access to reproductive healthcare.
December 22 – The Kansas City Chiefs announce they will leave Arrowhead Stadium for a new stadium in the state of Kansas by 2031.