2022 Copa Libertadores group stage
The 2022 Copa Libertadores group stage was played from 5 April to 26 May 2022. A total of 32 teams competed in the group stage to decide the 16 places in the final stages of the 2022 Copa Libertadores.
Draw
The draw for the group stage was held on 25 March 2022, 12:00 PYST, at the CONMEBOL Convention Centre in Luque, Paraguay.
Teams were seeded by their CONMEBOL Clubs ranking as of 16 December 2021, taking into account the following three factors:
- Performance in the last 10 years, taking into account Copa Libertadores and Copa Sudamericana results in the period 2012–2021.
- Historical coefficient, taking into account Copa Libertadores and Copa Sudamericana results in the period 1960–2011 and 2002–2011 respectively.
- Local tournament champion, with bonus points awarded to domestic league champions of the last 10 years.
For the group stage, the 32 teams were drawn into eight groups of four containing a team from each of the four pots. The defending champions Palmeiras were directly assigned as the top seed of Group A. The remaining teams were distributed into four pots according to their CONMEBOL Clubs ranking. Teams from the same association could not be drawn into the same group, excluding the four winners of the third stage, which were allocated to Pot 4 and could be drawn into the same group with another team from the same association.
| Pot 1 | Pot 2 | Pot 3 | Pot 4 |
;Notes
The following are the four winners of the third stage of qualifying which joined the 28 direct entrants in the group stage.
| Match | Third stage winners |
| G1 | Olimpia |
| G2 | Estudiantes |
| G3 | The Strongest |
| G4 | América Mineiro |
Format
In the group stage, each group is played on a home-and-away round-robin basis. The teams are ranked according to the following criteria: 1. Points ; 2. Goal difference; 3. Goals scored; 4. Away goals scored; 5. CONMEBOL ranking.
The winners and runners-up of each group advanced to the round of 16 of the final stages. The third-placed teams of each group entered the round of 16 of the 2022 Copa Sudamericana.
Schedule
The schedule of each matchday was as follows :| Matchday | Dates | Matches |
| Matchday 1 | 5–7 April 2022 | Team 4 vs. Team 2, Team 3 vs. Team 1 |
| Matchday 2 | 12–14 April 2022 | Team 2 vs. Team 3, Team 1 vs. Team 4 |
| Matchday 3 | 26–28 April 2022 | Team 2 vs. Team 1, Team 4 vs. Team 3 |
| Matchday 4 | 3–5 May 2022 | Team 3 vs. Team 2, Team 4 vs. Team 1 |
| Matchday 5 | 17–19 May 2022 | Team 1 vs. Team 2, Team 3 vs. Team 4 |
| Matchday 6 | 24–26 May 2022 | Team 1 vs. Team 3, Team 2 vs. Team 4 |
Groups
Group A
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Group B
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Group C
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Group D
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Group E
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Group F
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Group G
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Group H
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