2021 Columbus Challenger

The 2021 Columbus Challenger was a professional challenger level tennis tournament played on indoor hard courts. It was the tenth edition of the men's tournament which was part of the 2021 [ATP Challenger Tour] and the first edition of the women's event, that was part of 2021 WTA 125K series. It took place in Columbus, United States between 20 and 26 September 2021.

Champions

Stefan Kozlov def. Max Purcell 4–6, 6–2, 6–4.

Nuria Párrizas Díaz def. Wang Xinyu, 7–6, 6–3

Stefan Kozlov / Peter Polansky def. Andrew Lutschaunig / James Trotter 7–5, 7–6.

Wang Xinyu / Zheng Saisai def. Dalila Jakupović / Nuria Párrizas Díaz, 6–1, 6–1

¹ Rankings are as of September 13, 2021.

The following players received entry into the singles main draw as wildcards:

The following players received entry into the singles main draw as alternates:

The following players received entry into the singles main draw from the qualifying draw:

The following players received entry as lucky losers:

¹ Rankings are as of September 13, 2021.

The following players received entry into the singles main draw as wildcards:

The following player was accepted directly into the main draw using a protected or a special ranking:

The following players received entry into the singles main draw from the qualifying draw:

The following player received entry into the singles main draw as a lucky loser:

;Before the tournament

The following pairs received wildcards into the doubles main draw: