2021–22 Super League Greece 2

The 2021–22 Super League 2, known as Super League 2 betsson for sponsorship reasons, is the third season of the Super League 2, the second-tier Greek professional league for association football clubs, since the restructuring of the Greek football league system.
The season started on 6 November 2021 and ended in May 2022. The league will be conducted of 34 teams and two groups, this is due to the restructure and abolishment of the Football League. The league will also see the introduction of B Teams by Olympiacos, PAOK, AEK Athens and Panathinaikos. B Teams are ineligible for promotion and relegation.

Team changes

The following teams have changed division since the 2020–21 season.
Panachaiki, Ialysos, Santorini 2020, Orfeas Xanthi, Doxa Drama, Panionios, withdrew from the championship.

Promoted to Super League

Relegated to Gamma Ethniki

Relegated from Super League

Promoted from Football League

Promoted from Gamma Ethniki

B Teams

Team	City	Stadium	Capacity
AEL	Larisa	Alcazar Stadium	13,108
Almopos Aridea	Aridaia	Aridea Municipal Stadium	700
Anagennisi Karditsa	Karditsa	Municipal Stadium Karditsa	9,500
Apollon Larissa	Larisa	Filippoupoli Stadium	5,000
Apollon Pontus	Thessaloniki	Kalamaria Stadium	6,500
Iraklis	Thessaloniki	Kaftanzoglio Stadium	27,770
Kavala	Kavala	Anthi Karagianni Stadium	10,550
Niki Volos	Volos	Panthessaliko Stadium	22,700
Olympiacos B	Piraeus	Tavros Stadium	4,000
Olympiacos Volos	Volos	Neapoli Volos Municipal Stadium	2,500
Panserraikos	Serres	Serres Municipal Stadium	9,500
PAOK B	Thessaloniki	Makedonikos Stadium	8,100
Pierikos	Katerini	Katerini Municipal Stadium	4,995
Thesprotos	Igoumenitsa	Municipal Stadium Igoumenitsa	3,500
Trikala	Trikala	Trikala Municipal Stadium	15,000
Veria	Veria	Veria Stadium	7,000
Xanthi	Xanthi	Xanthi FC Arena	7,244

Team	City	Stadium	Capacity
AEK Athens B	Spata	Spata Training Centre	3,000
A.E. Kifisia	Kifissia	Municipal Kifisia Stadium	1,050
Asteras Vlachioti	Vlachiotis	Vlachiotis Municipal Stadium	600
Chania	Chania	Perivolia Municipal Stadium	4,527
Diagoras	Rhodes	Diagoras Stadium	3,700
Egaleo	Aigaleo	Stavros Mavrothalassitis Stadium	8,217
Episkopi	Lappa	Gallos Stadium	1,500
Ergotelis	Heraklion	Pankritio Stadium	26,240
O.F. Ierapetra	Ierapetra	Ierapetra Municipal Stadium	3,000
Irodotos	Heraklion	Municipal Nea Alikarnassos Stadium	3,000
Kalamata	Kalamata	Kalamata Municipal Stadium	5,613
Kallithea	Kallithea	Grigoris Lambrakis Stadium	6,300
Karaiskakis	Arta	Municipal Agioi Anargiroi Stadium	1,900
Levadiakos	Livadeia	Levadia Municipal Stadium	5,915
Panathinaikos B	Athens	Grigoris Lambrakis Stadium	6,300
Rodos	Rhodes	Diagoras Stadium	3,693
Zakynthos	Zakynthos	Zakynthians Olympic Champions Ground	2,000

Veria and Levadiakos played a 2 game title play-off on 8 and 15 May 2022.
Levadiakos were promoted to Super League 1. Veria participated in matches relegation play-offs to Super League 1 with the 13th team of 2021–22 Super League 1 — Lamia.