2-alkyn-1-ol dehydrogenase

In enzymology, 2-alkyn-1-ol dehydrogenase is an enzyme that catalyzes the chemical reaction below:
The two substrates of this enzyme are 1,4-butynediol and oxidised nicotinamide adenine dinucleotide. Its products are 4-hydroxybut-2-ynal, reduced NADH, and a proton.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 2-butyne-1,4-diol:NAD⁺ 1-oxidoreductase.