2,6-Dimethoxyphenethylamine
2,6-Dimethoxyphenethylamine, also known as DMPEA-5, is a drug of the phenethylamine family related to the psychedelic drug mescaline. It is one of the positional isomers of dimethoxyphenethylamine.
Its in-vitro metabolism and effects on cat behavior have been described. The drug showed no activity as a norepinephrine reuptake inhibitor or releasing agent in vitro. It is relatively unaffected by monoamine oxidase and is said to be behaviorally inactive in animals. The effects of 2,6-DMPEA in humans have not been reported and are unknown.
2,6-DMPEA was first described in the scientific literature by at least 1962. It was included as an entry in Alexander Shulgin's 2011 book The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds.
Notable derivatives of 2,6-DMPEA include the psychedelic and related drugs Ψ-2C-T-4, ψ-DOM, and CT-5172.