2,5-Dimethoxy-4-acetylamphetamine


2,5-Dimethoxy-4-acetylamphetamine is a serotonin 5-HT2 receptor modulator of the amphetamine and DOx families. Its affinities for the human serotonin 5-HT2 receptors are 80.5nM for the serotonin 5-HT2A receptor, 313nM for the serotonin 5-HT2B receptor, and 91.3nM for the serotonin 5-HT2C receptor. These affinities are much lower than those of many other DOx derivatives, such as DOB, but are very similar to those of 3,4,5-trimethoxyamphetamine. DOAc is a controlled substance in Canada under phenethylamine blanket-ban language.