2,4-Dimethoxyphenethylamine
2,4-Dimethoxyphenethylamine, also known as DMPEA-3, is a drug of the phenethylamine family related to the psychedelic drug mescaline. It is one of the positional isomers of dimethoxyphenethylamine.
The in-vitro metabolism of 2,3-DMPEA and its effects on cat behavior have been studied. The drug is known to act as a low-potency partial agonist of the serotonin 5-HT2A receptor. The effects of 2,4-DMPEA in humans have not been reported and are unknown.
2,4-DMPEA was first described in the scientific literature by at least 1964. It was included as an entry in Alexander Shulgin's 2011 book The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds.
NBOMe and NBOH derivatives with potent serotonin 5-HT2A receptor agonism, such as 24-NBOMe and 24-NBOH, have been synthesized and studied.