2,3,6-Trimethoxyphenethylamine


2,3,6-Trimethoxyphenethylamine, also known as TMPEA-5 or as 2C-TMA-5, is a chemical compound of the phenethylamine family related to mescaline. It is one of the possible positional isomers of trimethoxyphenethylamine and is a positional isomer of mescaline. According to Alexander Shulgin in his book PiHKAL, 2,3,6-TMPEA is not known to have ever been tested in humans. It is either a competitive substrate or inhibitor of monoamine oxidase. The chemical synthesis of 2,3,6-TMPEA has been described. 2,3,6-TMPEA was first described in the scientific literature by J. R. Merchant and A. J. Mountwala in 1958. As a positional isomer of mescaline, it is a Schedule I controlled substance in the United States. The drug is a controlled substance in Canada under phenethylamine blanket-ban language.