| 1 | Jeff Burroughs | Washington Senators | OF | Long Beach, California |
| 2 | J. R. Richard | Houston Astros | RHP | Ruston, Louisiana |
| 3 | Ted Nicholson | Chicago White Sox | 3B | Laurel, Mississippi |
| 4 | Randy Sterling | New York Mets | RHP | Key West, Florida |
| 5 | * Alan Bannister | California Angels | SS | Buena Park, California |
| 6 | Mike Anderson | Philadelphia Phillies | 1B | Timmonsville, South Carolina |
| 7 | Paul Ray Powell | Minnesota Twins | OF | Arizona State University |
| 8 | Terry McDermott | Los Angeles Dodgers | C | West Hempstead, New York |
| 9 | Don Stanhouse | Oakland Athletics | RHP | DuQuoin, Illinois |
| 10 | Bob May | Pittsburgh Pirates | RHP | Merritt Island, Florida |
| 11 | Charlie Spikes | New York Yankees | 3B-OF | Bogalusa, Louisiana |
| 12 | Gene Holbert | Atlanta Braves | C | Campbelltown, Pennsylvania |
| 13 | Noel Jenke | Boston Red Sox | OF | University of Minnesota |
| 14 | Don Gullett | Cincinnati Reds | LHP | Lynn, Kentucky |
| 15 | Alvin McGrew | Cleveland Indians | OF | Fairfield, Alabama |
| 16 | Roger Metzger | Chicago Cubs | SS | St. Edward's University |
| 17 | Don Hood | Baltimore Orioles | LHP | Florence, South Carolina |
| 18 | Mike Phillips | San Francisco Giants | SS | Irving, Texas |
| 19 | John Young | Detroit Tigers | 1B | Redding, California |
| 20 | Richard Minott | St. Louis Cardinals | LHP | Covina, California |
| 21 | Gorman Thomas | Seattle Pilots | SS | Charleston, South Carolina |
| 22 | Balor Moore | Montreal Expos | LHP | Deer Park, Texas |
| 23 | * John Simmons | Kansas City Royals | SS | Childersburg, AL |
| 24 | Randy Elliott | San Diego Padres | 1B | Camarillo, California |