1513 in science

The year 1513 in science and technology included a number of events, some of which are listed here.

Exploration and cartography

March 27 – Juan Ponce de León becomes the first European definitely known to sight the modern-day territory of the United States, specifically Florida, mistaking it for another island. His expedition lands on April 2.
May – Portuguese explorer Jorge Álvares lands on Lintin Island in the Pearl River estuary.
September 26 – Vasco Núñez de Balboa, "silent upon a peak in Darién", first sees what will become known as the Pacific Ocean.
Portuguese land on Ambon Island.
Piri Reis map compiled.
Publication in Oppenheim of Johannes Stöffler's treatise on the construction and use of astrolabes, Elucidatio fabricae ususque astrolabii.

Eucharius Rösslin publishes Der Rosengarten, an obstetrics manual primarily for midwives written in German which will be widely translated and circulated in Europe.