101 South Hanley

101 South Hanley is a tall modern office building located on 101 South Hanley Road in Downtown Clayton, Missouri. It was built in 1986 and has 19 floors. When it was built it was the 3rd-tallest building in Clayton, as of January 2026 it is the 6th-tallest building in Clayton. Notable tenants include CoStar, First American Title Insurance Company, and the Meridian Land Group.
The building currently has 360,505 rentable sq footage.
In 2015, Oculus was selected to lead the redesign and rebrand of the tower by KBS, who bought it in 2014 from Duke Realty for $62.25 million dollars. The enhancements were expected to cost $6.5 million dollars.