Zamicastat
Zamicastat is a peripherally selective dopamine β-hydroxylase inhibitor which is under development for the treatment of pulmonary arterial hypertension and heart failure. It is structurally related to etamicastat and is said to be an improved version of this drug. As of July 2022, zamicastat is in phase 2 clinical trials for PAH and phase 1 clinical trials for heart failure. However, no recent development has been reported for heart failure.