Wyoming Highway 221Wyoming Highway 221 was a east-west Wyoming State Road known as Fox Farm Road located in southeastern Cheyenne.Route descriptionWyoming Highway 221 traveled from I-25 Business/US 85/US 87 Business to Wyoming Highway 212. Highway 221 paralleled Interstate 80 about one-half mile south of the Interstate and served residential and commercial areas. The route was decommissioned in 2009; all state route marker signs have been removed, and the route no longer appears on the Wyoming Official State Highway Map.