William Wilkins
William Wilkins may refer to:
- William Wilkins (architect), British architect and archaeologist
- William Wilkins (American politician), American politician from Pennsylvania; served in both houses of Congress and as U.S. Secretary of War
- William Wilkins (educator), Australian teacher and co-founder of Fort Street High School
- William Glyde Wilkins, head of W.G. Wilkins Company, an architectural and engineering firm in Pittsburgh, Pennsylvania
- William Henry Wilkins, English writer
- William J. Wilkins (judge), American lawyer and judge from the state of Washington
- William Wilkins (British politician), British Labour Party MP for Bristol South, 1945–1970
- Willie Wilkin, American football player
- William J. Wilkins (architect), American architect who worked in the Carolinas
- William Walter Wilkins, former United States federal judge
- Billy Wilkins, Christian musician with the band Third Day