William Simms
William, Willie, Will or Bill Simms may refer to:
- William Simms (instrument maker), British astronomical instrument maker
- William E. Simms, American politician
- William Gilmore Simms, American writer and historian
- William Knox Simms, Australian businessman and politician
- Willie Simms, American jockey
- Will Simms II, Survivor contestant
- Bill Simms, American baseball player