William Sadler

• William Sadler , Irish landscape painter
• William Sadler , American sailor and Medal of Honor recipient
• William Sadler , American film and television actor
• William S. Sadler, American surgeon and psychiatrist
• William Richard Sadler, American politician from Pennsylvania
• Billy Sadler, American baseball pitcher
• Bubby Sadler, American Negro league baseball player
• Bill Sadler , Canadian race car designer, electrical and electronics engineer, aviation designer