William Rutherford
William Rutherford may refer to:
- Bill Rutherford, British professor of biochemistry
- Bill Rutherford, Scottish footballer
- Bill Rutherford, Oregon politician
- William Gunion Rutherford, Scottish scholar
- William Rutherford , English mathematician
- William Rutherford , British physiologist
- Sir William Rutherford, 1st Baronet, British politician, MP for West Derby and Edge Hill
- Willie Rutherford, Australian football player