William Reese
William Reese may refer to:
- William J. Reese , architect in The Hamptons area of New York
- William J. Reese, historian of education and professor at the University of Wisconsin–Madison
- William L. Reese, American professor of philosophy
- William Oliver Reese, American sailor who murdered a Japanese woman
- James W. Reese, American soldier and Medal of Honor recipient, went by his middle name "William"
- William Reese, 4th of five victims of serial killer Andrew Cunanan
- Red Reese, American college basketball coach and athletic director
- William S. Reese, antiquarian bookseller