William Houghton

• William Houghton (bishop), Roman Catholic Archbishop of Dublin, Ireland
• William Houghton (naturalist), author of British Fresh-Water Fishes
• William Houghton (American football), American football coach
• William Henry Houghton, president of the Moody Bible Institute
• William Stanley Houghton, British playwright
• William Vasey Houghton, Australian politician
• William Houghton (cricketer), Zimbabwean cricketer