William Erskine
William Erskine may refer to:
- William Erskine (master of Charterhouse), master of Charterhouse Hospital
- William Erskine (died 1697), member of the Parliament of Scotland for Culross
- William Erskine (1691–1754), member of the Parliament of Great Britain for Perth Burghs
- Sir William Erskine, 1st Baronet, British Army officer
- William Erskine, Lord Kinneder, Scottish scholar and songwriter
- Sir William Erskine, 2nd Baronet, British Army officer and Member of Parliament
- William Erskine (historian), Scottish orientalist and historian
- William Erskine (diplomat), British ambassador