William DuBois
William DuBois may refer to:
- William DuBois (architect), American architect and politician based in Cheyenne, Wyoming
- William Dubois (usher), Chief Usher of the White House, 1881–1902
- William DuBois (writer), American playwright, novelist, and editor of The New York Times Book Review
- William Edward Burghardt Du Bois, American sociologist, historian, and civil rights activist
- William H. Dubois, Vermont businessman and political figure
- William Pène du Bois, French-American author and illustrator